Healthcare Technology

Medical Devices Development & Clinical Application

Description:

This course is an introduction to the medical device field, with emphasis on the ways in which chemical engineering processes provide the foundation for many device-related therapies. The course involves the application of several fundamental chemical engineering principles, including those related to mass transfer, separations, and fluid flow, to devices used for extracorporeal therapies and other treatments.

Course Objectives:

• Assess the mechanisms of blood-surface interactions defining the biocompatibility of an extracorporeal device
• Evaluate the influence of extracorporeal membrane structure and material on transport properties (diffusion, convection, and ultrafiltration) and the overall effect on device performance
• Explain the implications of different blood flow regimes (laminar versus turbulent) on both the removal properties of membrane-based devices and the function of different vascular access devices
• Analyze device-related and patient-related (physiologic) parameters required for kinetic modeling of different dialysis therapies.
• Apply fundamental chemical engineering principles to provide a quantitative basis for treatments of specific clinical disorders, including end-stage renal disease (ESRD), acute kidney injury (AKI), sepsis, cardiac failure, and respiratory failure
• Characterize the major components of a medical device company and the manner in which these different functions interact during the pre-market and post-market phases of product development
• Apply important principles of project management, verification/validation, and lean manufacturing to medical device development